Peak Purity Assessments in Chromatography: A Case Study of Chlorpromazine Hydrochloride

Authors

  • Erisa Owino Department ofPharmacy, Makerere Medical School, Makerere University, P.0. Box 7072, Kampala, Uganda

Keywords:

Chlorpromazine hydrochloride, chlorpromazine impurities and chromatographic peak purity

Abstract

This work examines the applicability of different peak purity and/or homogeneity
deconvolution algorithms for the evaluation of chromatographic purity and/or
homogeneity in chlorpromazine hydrochloride, in the order of the algorithm's
increasing complexity. The methods are examined for usefulness with a view to
possible routine application in a busy quality assurance laboratory include
chromatographic peak assessment, spectral normalization, absorbance ratios and
chromatographic derivatives.

References

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Published

2020-05-21

Issue

Vol. 5 No. 3 (2002): September-December 2002

Section

Articles

How to Cite

Peak Purity Assessments in Chromatography: A Case Study of Chlorpromazine Hydrochloride. (2020). The East and Central African Journal of Pharmaceutical Sciences, 5(3), 55-59. http://jsep.uonbi.ac.ke/ojs/index.php/ecajps/article/view/366